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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AXIN1
All Species:
21.82
Human Site:
Y375
Identified Species:
43.64
UniProt:
O15169
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15169
NP_003493.1
862
95635
Y375
L
P
H
I
P
R
T
Y
R
V
P
K
E
V
R
Chimpanzee
Pan troglodytes
XP_001152990
821
90810
H375
L
P
H
I
P
R
T
H
R
V
P
K
E
V
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_852321
867
95820
Y375
L
P
H
I
P
R
T
Y
R
M
P
K
E
I
R
Cat
Felis silvestris
Mouse
Mus musculus
O35625
863
96295
Y375
L
P
H
I
P
R
T
Y
R
M
P
K
E
I
R
Rat
Rattus norvegicus
O70239
827
92266
Y375
L
P
H
I
P
R
T
Y
R
M
P
K
E
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508740
844
93228
R357
V
S
L
P
H
F
P
R
T
H
R
L
P
K
E
Chicken
Gallus gallus
O42400
841
94913
Y375
L
P
H
I
P
R
T
Y
R
M
P
K
D
I
H
Frog
Xenopus laevis
Q9YGY0
842
94441
Y375
L
P
H
I
P
R
T
Y
H
M
P
K
D
I
H
Zebra Danio
Brachydanio rerio
P57094
835
94310
N378
L
P
H
I
P
R
T
N
R
I
P
K
D
I
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V407
745
81700
P348
A
H
G
Y
V
Y
N
P
S
T
T
N
T
S
Y
Honey Bee
Apis mellifera
XP_001120373
693
78297
L309
V
S
R
Q
D
S
E
L
Q
S
L
S
S
D
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781992
855
95982
H359
Q
N
G
K
V
M
T
H
L
P
C
P
R
A
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.6
N.A.
86.6
N.A.
87
84.2
N.A.
43.2
73
67.5
64
N.A.
21.8
27.2
N.A.
33
Protein Similarity:
100
95.1
N.A.
91.2
N.A.
91.1
88.1
N.A.
59.4
82.9
79.4
74.8
N.A.
38
42.4
N.A.
50.3
P-Site Identity:
100
93.3
N.A.
86.6
N.A.
86.6
86.6
N.A.
0
73.3
66.6
66.6
N.A.
0
0
N.A.
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
6.6
93.3
86.6
86.6
N.A.
0
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
0
0
0
0
9
0
0
0
0
0
0
0
25
9
0
% D
% Glu:
0
0
0
0
0
0
9
0
0
0
0
0
42
0
9
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
9
67
0
9
0
0
17
9
9
0
0
0
0
34
% H
% Ile:
0
0
0
67
0
0
0
0
0
9
0
0
0
50
0
% I
% Lys:
0
0
0
9
0
0
0
0
0
0
0
67
0
9
0
% K
% Leu:
67
0
9
0
0
0
0
9
9
0
9
9
0
0
0
% L
% Met:
0
0
0
0
0
9
0
0
0
42
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
9
9
0
0
0
9
0
0
0
% N
% Pro:
0
67
0
9
67
0
9
9
0
9
67
9
9
0
0
% P
% Gln:
9
0
0
9
0
0
0
0
9
0
0
0
0
0
0
% Q
% Arg:
0
0
9
0
0
67
0
9
59
0
9
0
9
0
42
% R
% Ser:
0
17
0
0
0
9
0
0
9
9
0
9
9
9
0
% S
% Thr:
0
0
0
0
0
0
75
0
9
9
9
0
9
0
0
% T
% Val:
17
0
0
0
17
0
0
0
0
17
0
0
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
9
0
50
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _